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1 Conceptual aspects of self and nonself discrimination - PMC
Innate immunity not only recognizes nonself antigens, but also utilizes more sophisticated mechanisms of recognition. Modification of self proteins by microbial ...
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2 Self versus Non-Self | BioNinja
The immune system has the capacity to distinguish between body cells ('self') and foreign materials ('non-self'). It will react to the presence of foreign ...
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3 Your Immune System: The Basics -
All of your body's cells carry specific proteins on their surfaces that help the immune system recognize them as “self.” That's why the immune ...
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4 Decoding the Patterns of Self and Nonself by the Innate ...
The innate immune system evolved several strategies of self/nonself discrimination that are based on the recognition of molecular patterns demarcating ...
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5 Essentials of Immunology | Immuno-Oncology for HCPs
Differentiating self from nonself is a hallmark of the immune response. The immune system is a network of tissues, cells, and signaling molecules that work ...
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6 The Immune System and Primary Immunodeficiency
The immune system is composed of a variety of different cell types and proteins. ... their own cells or tissues as if these cells were foreign, or non-self.
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7 Immune system physiology | NCLEX-RN | Khan Academy
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8 Natural Autoantibodies: An Undersugn Hero of the Immune ...
The cardinal feature of an autoimmune disease is the unfolding of an excessive self-reactive, antigen-driven, immune response. The emergence of ...
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9 Autoimmune disorders: MedlinePlus Medical Encyclopedia
An autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue by mistake. There are more than 80 ...
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10 Chapter 2 How the Immune System Achieves Self–Nonself ...
The immune system accomplishes self–nonself discrimination, in part, by employing cell‐surface recognition molecules which, when activated by nonself ligands ...
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11 How Lupus Affects the Immune System
In lupus, the immune system begins to recognize and attack “self.” In other words, the cells of the immune system begin to injure the body's own tissues.
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12 Recognition Of Self Vs Non Self Autoimmune Diseases
The lymphocytes of the immune system form antibodies to fight non-self antigens. Sometimes, the lymphocytes create antibodies for self-antigens known as ...
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13 An introduction to immunology and immunopathology
The primary functions of the adaptive immune response are: the recognition of specific “non-self” antigens, distinguishing them from “self” ...
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14 Self-Tolerance - GenScript
Self-tolerance is the ability of the immune system to recognize self-produced antigens as a non-threat while appropriately mounting a response to foreign ...
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15 COVID-19 Can Trigger Self-Attacking Antibodies - Cedars-Sinai
Infection with the virus that causes COVID-19 can trigger an immune response that lasts well beyond the initial infection and recovery—even ...
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16 What Happens When the Immune System Does Not Work ...
Sometimes the immune system does not work properly due to immune deficiencies ... immune responses, such as allergies; or immune responses to one's self, ...
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17 How the Immune System Recognizes Self and Nonself
The immune system recognizes and distinguishes a variety of structural features of self and nonself components. The latter actually include almost everything ...
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18 Immune recognition of self and non-self explored in new study
In a new study, ASU researcher Joshua LaBaer and his colleagues explore components of the immune system known as autoantibodies.
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19 Autoimmune disorders - Better Health Channel
An autoimmune disorder occurs when a person's immune system mistakenly ... The 'self-attacking' T cells that escape destruction may be activated by a ...
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20 How the immune system works to protect the host from infection
The self-referential nature of adaptive immunity, which is based on antigen-specific responses of T and B lymphocytes, is now well established for T cells, and, ...
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21 Autoimmune Diseases: Types, Symptoms, Causes & More
An autoimmune disease is a condition in which your immune system attacks your body. We'll explain the causes and complications of autoimmune disease and how ...
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22 immune system disorder - Autoimmune disorders | Britannica
Nevertheless, an immune response to self, called autoimmunity, can occur, and some of the ways that self-directed immune responses cause damage have been ...
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23 The Innate vs. Adaptive Immune Response - Healio
The second line of defense against non-self pathogens is called adaptive immune response. Adaptive immunity is also referred to as acquired immunity or specific ...
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24 Autoimmunity - Wikipedia
In immunology, autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other normal body constituents.
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25 Definition of Autoimmunity & Autoimmune Disease
These components are called autoantigens or self-antigens and typically consist of ... Cancer patients who are treated with inhibitors of immune checkpoints ...
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26 Autoimmune Diseases: What Are They? Who Gets Them?
WebMD explains immune system disorders like asthma and rheumatoid arthritis, including causes and treatments.
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27 Autoimmune Diseases: Causes, Symptoms, What Is It ...
Autoimmune diseases like lupus, multiple sclerosis, rheumatoid arthritis and psoriasis happen because your immune system attacks your body ...
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28 About Autoimmunity
The immune system normally can distinguish “self” from “non-self.” Some lymphocytes are capable of reacting against self, resulting in an autoimmune reaction.
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29 Autoimmunity | In Defense of Self: How the Immune System ...
This touches on the important issue of immune tolerance. Breakage of self-tolerance results in autoimmune disease. This chapter looks at a number of human ...
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30 Immune System (for Parents) - Nemours KidsHealth
How Does the Immune System Work? · Innate immunity: Everyone is born with innate (or natural) immunity, a type of general protection. · Adaptive immunity: ...
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31 In Defense of Self: How the Immune System Really Works
In Defense of Self: How the Immune System Really Works: 9780195335552: Medicine & Health Science Books @
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32 The Main Principles of Adaptive Immune System Function ...
The main forms of physiological activity of the immune system are based on the intrinsic abilities of self-identification, selfmaintenance, self-regulation, ...
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33 Researchers find possible cause for self-destructive immune ...
Autoimmune diseases, in which the body's own immune system attacks healthy tissue, can be life-threatening and can impact all organs.
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34 Study links severe COVID-19 to increase in self-attacking ...
In some cases, the presence of those newly detected autoantibodies may reflect an increase, driven by the immune response, of antibodies that ...
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35 The immune system and immunisation
Each pathogen has unique distinguishing components, known as antigens, which enable the immune system to differentiate between 'self' (the body) and 'non-self' ...
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36 Boot Camp for the Immune System | Harvard Medical School
To perform its myriad functions, the immune system must, above all, differentiate between self and non-self—a remarkable selective ability ...
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37 Long COVID: How researchers are zeroing in on the self ...
A new study finds that misdirected immune responses can persist for months ... To prevent self-destruction, the immune system relies on an ...
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38 Autoimmune diseases may be side effect of a strong immune ...
The immune system has much at its disposal, including specialist ... the participants with high levels of self-reactive antibodies had on ...
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39 Understanding the Immune System - SITC connectED
Cells with self-antigens are typically not a threat. Invading germs, however, do not originate in the body and so do not carry self-antigens; instead, they ...
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40 What is Immune Tolerance? - Anokion
A healthy immune system targets only foreign antigens, not the body's own cells (self-antigens). The immune system's recognition of self-antigens is called ...
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41 Definition of autoimmune disease - NCI Dictionary of Cancer ...
A condition in which the body's immune system mistakes its own healthy tissues as foreign and attacks them. Most autoimmune diseases cause inflammation that ...
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42 Immunology: How Does the Adaptive Immune System Work?
The adaptive immune response uses antigen-specific receptors to detect foreign ... critical jobs of the immune system is to distinguish self from non-self.
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43 Why Your Immune System Doesn't Eat You Alive
As a solution, some scientists proposed that the body wipes out those self-reactive cells while the immune system is developing. Subsequent ...
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44 Understanding the Immune System: How it works - IMGT
Contents. 1 Introduction. 2 Self and Nonself. 3 The Structure of the Immune System. 7 Immune Cells and Their Products. 19 Mounting an Immune Response.
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45 The immune system: Cells, tissues, function, and disease
The immune system defends the body from invaders such as viruses, bacteria, and foreign bodies. Find out how it works, what can go wrong, and how to boost ...
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46 Self and Non-self Discrimination of Intracellular Membranes ...
Figures · Overview · The Innate Immune System Recognizes and “Marks” Pathogen-Containing Vacuolar Membranes and Cytosolic Bacteria for Autophagic ...
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47 Self recognition by the immune system
In each organism, the immune system must acquire the ability to distinguish self from nonself. Experiments in T cell receptor transgenic mice indicate that this ...
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48 Autoimmune diseases | Office on Women's Health
At the core of the immune system is the ability to tell the difference between self and nonself: what's you and what's foreign. A flaw can make ...
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49 Immune system - NHS inform
Immune system. Illnesses, deficiencies and disorders of the immune system. Allergies. Learn more about allergies and their symptoms and treatments ...
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50 The Immune System & Its Link to Rheumatic Disease
This leads to illnesses called autoimmune (self-immune) diseases such as rheumatoid arthritis (inflammation of the joints), systemic lupus erythematosus ( ...
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51 People Who Are Immunocompromised - CDC
Learn about how to protect yourself from COVID-19 if you are ... Some people who are immunocompromised (have a weakened immune system) are more likely to ...
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52 Weakened Immune System - Penn Medicine
If you're often sick, feel fatigued or have other nagging symptoms you can't figure out, you may have a weakened immune system.
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53 Types of Antigens | Non-Self Antigens, Self-Antigens & Allergens
The antigen-presenting cells will only present non-self antigens to the adaptive immune system cells that will stimulate an aggressive immune ...
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54 20.2: Introduction to the Immune System - Biology LibreTexts
Host vs. Pathogen · What is the Immune System? · Self vs. Non-Self · Antigens and Antibodies · Immune Surveillance · Lymphatic System · Review.
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55 How the immune system achieves self ... - Semantic Scholar
Semantic Scholar extracted view of "How the immune system achieves self-nonself discrimination during adaptive immunity." by Hong Jiang et al.
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56 Rogue antibodies could be driving severe COVID-19 - Nature
Evidence is growing that self-attacking 'autoantibodies' could be the ... Immune-system signalling proteins called cytokines can ramp up to ...
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57 What is Immune Tolerance & Types of Immunological Tolerance
Self-tolerance refers to the ability of the immune system to recognize—and therefore not respond against—self-produced antigens. If the immune system loses ...
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58 Suppressed Immune System: What Is It, Causes, and More
This occurs when the immune system produces self-targeting antibodies, which cannot distinguish between self and non-self and will therefore mistakenly ...
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59 How the hnmune System Learns about Self - JSTOR
The pep tides are transported to the cell surface and presented to the immune system. The antigen receptors of killer T cells allow them to recognize the viral ...
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60 How the Immune System Recognizes Self and Nonself
Edited by D. Kitamura. Springer ISBN #978-4-431-73883-1. This is an excellent monograph on the immune system and how it works. The book aims at exploring ...
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61 What Does it Mean to Have a Strong Immune System?
A strong immune system has both powerful adaptive and innate immunity; both work together to protect the self from foreign invaders.
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62 Does the Immune System Act as a Self-Organized System in ...
Does the Immune System Act as a Self-Organized System in Multiple Sclerosis? · Bahareh Safarbali, M.Sc. student , · Fatemeh Hadaeghi, Ph.D.
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63 What Happens When Your Immune System Works Against ...
The mechanism by which the immune cells differentiate between self and non-self antigens "Foreign antigens" is by specific recognition molecules ...
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64 The Immune System Click & Learn Educator Materials
What type of condition may be caused by T cells that bind to self-antigens? An autoimmune disease (such as rheumatoid arthritis). 2. How does the body replace ...
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65 Autoimmune hepatitis - Symptoms and causes - Mayo Clinic
This type of hepatitis occurs when your immune system attacks your liver with destructive antibodies. Immune-suppressing medication is the ...
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66 Tolerance - Autoimmune disease - TeachMePhysiology
Normally, immune cells only react against foreign antigens, and healthy cells displaying self-antigens do not trigger an immune response.
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67 Your Dog's Immune System | Morris Animal Foundation
The innate immune system finds problems by knowing what normal self looks like and recognizing that these cells or organisms don't fit the ...
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68 The Immune System - CancerQuest
, viruses or other organisms that can invade our bodies. A more subtle distinction between self and non-self occurs in the recognition of cancer cells by the ...
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69 23.2. Adaptive Immune Response – Concepts of Biology
An antigen is a foreign or “non-self” macromolecule that reacts with cells of the immune system. Not all antigens will provoke a response.
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70 Bridging autoinflammatory and autoimmune diseases
Autoimmunity is used to cause by impairment of adaptive immunity alone, ... system result in loss of immune tolerance against self-tissues, ...
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71 Innate vs Adaptive Immunity - Technology Networks
How does the immune system tell self from non-self? In humans, all nucleated cells express distinctive surface molecules called major ...
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72 Immunologic Tolerance and Autoimmunity: Self–Nonself ...
One of the remarkable properties of the normal immune system is that it can react to an enormous variety of microbes but does not react ...
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73 Causes/Inheritance - Myasthenia Gravis (MG) - Diseases
Normally (A), the immune system releases antibodies to attack foreign invaders, ... stimulating the immune system to unwittingly attack the self-protein.
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74 What Is the Immune System? - Diabetes Education Online
Additionally, the immune response allows some foreign material and normal cells for each individual (or “self”) to be tolerated. The balance between a ...
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75 Overview of autoimmunity - UpToDate
Autoimmune diseases are characterized by a pathologic response to self- or autoantigens; these responses can be categorized as autoimmunity ...
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76 Three Important Characteristics to Adaptive Immunity
This property refers to the ability of the immune system to recognize non-self antigens and respond in a specific manner to them, rather than responding in ...
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77 How does the immune system self-regulate? - BioTechniques
How does the immune system self-regulate? · Regulatory T cells control the immune reaction from killer cells to ensure healthy tissue surrounding ...
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78 How the immune system protects against infection - Inivos
In order to destroy invading pathogens and protect us from infection, the immune system has to be able to differentiate between self antigens, ...
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79 Innate Immune Response Triggers Lupus-like Autoimmune ...
Remarkably, this illness is precipitated by an innate immune response to altered self glycans that mimic molecular patterns found on pathogens.
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80 The immune system which works against self is
Self immune system · Autoimmunity · Specific immunity · None of the above · Autoimmunity is the system of immune responses of an organism against its own cells and ...
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81 The immune system and cancer | EdCaN
The immune system has several functions such as defense against foreign organisms, ... These abnormal tumour proteins mark cancer cells as 'non-self'.
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82 Course #38431: Pathophysiology: The Immune System - NetCE
Self-Assessment Questions. 1 . Immunity can be defined as. A), the invasion and multiplication of micro-organisms.
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83 Autoimmune diseases in dermatology - DermNet
The immune system is made up of the cells, molecules, and structures that ... Autoimmunity is an immune response against the self that usually involves T ...
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84 What happens in autoimmune diseases like lupus?
In lupus, something goes wrong with the immune system, which is the part of the body that ... that attack and destroy healthy tissue ("auto" means "self").
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85 How unchecked alarms can spark autoimmune disease
Cornell researchers have identified a signaling mechanism in immune-system cells that may contribute to this mistake, opening the door for ...
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86 T cells, B cells and the immune system
It generally recognizes patterns in cells that help sort self from pathogens. For example, when an innate immune cell comes into contact with a ...
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87 Immune System for the MCAT: Everything You Need to Know
Learn key MCAT concepts about the immune system, plus practice questions and answers. ... c) Recognition of self and non-self ...
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88 The Immune System
The immune system is a complex network of organs containing cells that ... is an autoimmune (literally "self-immune") disease in which the immune system ...
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89 New way viruses trigger autoimmunity discovered
In mice, roseolovirus disrupts immune cells' process of learning self-recognition. by Tamara Bhandari•February 28, 2022. Bernard Kramarsky.
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90 The Immune Response: A Cellular War | Let's Talk Science
These are diseases where your body's immune system mistakes self cells for non-self cells. So, the body of someone with an autoimmune disease ...
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91 Why does the immune system attack itself? - MS Australia
MS arises when the immune system attacks the myelin sheath, an insulating coating ... the two scenarios while also distinguishing between self and non-self.
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92 Immune System | Biology for Majors II - Lumen Learning
Our immune systems offer us protection against a world full of pathogens. ... The presentation of non-self cells can then trigger the immune system.
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93 White Blood Cells and Innate and Acquired Immunity
Cells with antigens that the immune system recognizes as the self are left alone, while a non-self antigen cell will deploy our immunity, which ...
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94 Self-Tolerance (Immune System) - Draw It to Know It
Self-Tolerance • Failure of self-tolerance results in autoimmune disorders, in which abnormal immune cells provoke a damaging immune response to otherwise ...
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95 Adaptive immune system - Knowledge @ AMBOSS
Adaptive (acquired) immunity is a part of the immune system that provides an antigen-specific response following exposure to a microbial ...
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